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Why is Chromosomal Microarray Analysis a Powerful Genetic Screening Test?

Chromosomal Microarray Analysis

Genes2Me by Genes2Me
September 16, 2022
in Health
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Chromosomal Microarray Analysis

Chromosomal Microarray Analysis in India - Genes2Me

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Chromosomal Microarray Analysis in India
Who is Chromosomal Microarray Analysis Recommended for?

The chromosomal microarray analysis test is one of the most popular tests recommended for children with developmental delays, congenital disabilities, autism spectrum disorder etc. Comprehensive genetic testing helps detect the presence of chromosomal abnormalities, like detecting an extra portion or a missing portion of a chromosome. It is an affordable analysis and screening technique to detect copy number variations in a chromosomal makeup and identify the reason for an underlying genetic condition or disease. 

Powerful Genetic Test to Detect Chromosomal Abnormality

 is available across the majority of the state-of-the-art and advanced molecular diagnostic labs. The powerful microarray test is a non-invasive method that analyses an individual’s genome and identifies chromosomal abnormalities like translocation

Chromosomal Microarray Analysis
Chromosomal Microarray Analysis in India – Genes2Me

, deletions, duplication’s, and extra chromosomes. It helps in detecting the copy number variants, the test help in the detection of autism spectrum disorder, developmental delays, seizures etc. It is a chip-based testing platform that simultaneously allows high-volume, automated DNA pieces analysis. The technique uses labels or probes that bind to specific chromosome regions, and a comparative analysis is made with the reference sample. 

Chromosomal Microarray Analysis and what it helps in detection

The Chromosomal microarray Analysis is used as one of the most accurate first-trimester screening for Trisomies 21 and 18. It is a recommended prenatal genetic testing that helps detect chromosomal abnormality or copy number variant as early as the first trimester. As a front line high-resolution diagnostic procedure, it helps identify sub-microscopic micro-deletions, micro-duplication’s, trisomy, recurring pregnancy loss, and ultrasound abnormalities. CMA is a technique that helps detect even unbalanced rearrangements of chromosomes like translocation.

The CMA test help in accurately detecting the presence of (Down Syndrome) and Trisomy 18 (Edward’s Syndrome). The prenatal CMA compares specific regions of an unborn baby’s DNA to a normal genome. Detection of the micro duplication and micro deletion in the chromosome can lead to genetic disorders and intellectual or physical abnormalities in the newborn child. A popular Down Syndrome screening test provides accurate information on Trisomy 21 during the first trimester. 

Who is Chromosomal Microarray Analysis Recommended for?

  • It helps identify copy number variants which include micro deletion and micro duplication.
  • This test is recommended for women with recurring pregnancy loss and is a powerful prenatal screening test. Chromosomal abnormality is one of the most common reasons for recurring pregnancy loss.
  • Abnormal findings in the ultrasound indicate a potential risk for developing a genetic abnormality.
  • It is a highly recommended prenatal test for women over 35 and above of maternal age.
  • The powerful test help in identifying the genetic reason for development delays, intellectual delay and a range of autism spectrum disorders.
Chromosomal Microarray Analysis
Chromosomal Microarray Analysis and what it helps in detection

Cost of

With the establishment of advanced molecular diagnostics labs and the availability of the test, the prices have significantly reduced. The price may vary from location to lab but mostly starts from Rs 20,000 in India. The time is taken to prepare the report in nearly three weeks. All established molecular diagnostic labs by certified genetic counsellors provide pre-and post-genetic counselling.

Tags: ChromosomalChromosomal MicroarrayDown Syndrome ScreeningGeneticGenetic TestGenetic TestingmicroarrayNIPS TestNIPT Test
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